PROTAC VEGFR-2 degrader-1
Product Specifications
CAS Number
2601594-19-6
Target
PROTACs, VEGFR, Others
Related Pathways
Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis, Others
Bioactivity
PROTAC VEGFR-2 Degrader-1 (PROTAC-1), a specific degrader of PROTAC VEGFR-2, demonstrates minimal inhibition of VEGFR-2 (IC50 > 1 μM) and exhibits low anti-proliferative effects on EA.hy926 cells (IC50 > 100 μM) [1].
Smiles
CC(C)c1cccc(NC(=O)Nc2cccc(c2)-c2cccc3n(nc(N)c23)C(=O)CCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)c1
Molecular Formula
C52H61N9O6S
Molecular Weight
940.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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