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PROTAC VEGFR-2 degrader-1

Product Specifications

CAS Number

2601594-19-6

Target

PROTACs, VEGFR, Others

Related Pathways

Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis, Others

Bioactivity

PROTAC VEGFR-2 Degrader-1 (PROTAC-1), a specific degrader of PROTAC VEGFR-2, demonstrates minimal inhibition of VEGFR-2 (IC50 > 1 μM) and exhibits low anti-proliferative effects on EA.hy926 cells (IC50 > 100 μM) [1].

Smiles

CC(C)c1cccc(NC(=O)Nc2cccc(c2)-c2cccc3n(nc(N)c23)C(=O)CCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)c1

Molecular Formula

C52H61N9O6S

Molecular Weight

940.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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