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Aminobenzenesulfonic auristatin E

Product Specifications

CAS Number

1800462-99-0

Target

Microtubule Associated|||Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling

Bioactivity

Aminobenzenesulfonic auristatin E is a potent antitumor agent-linker conjugate for Antibody-Drug Conjugates (ADC) . It utilizes Auristatin E (a cytotoxic tubulin modifier) connected through the ADC linker, Aminobenzenesulfonic [1], to exhibit significant antitumor activity.

Smiles

[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)NS(=O)(=O)c1ccc(N)cc1

Molecular Formula

C37H64N6O8S

Molecular Weight

753

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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