3'Ome-m7GpppAmpG

3'Ome-m7GpppAmpG, a trinucleotide cap analogue with a locked nucleic acid (LNA) molecule, demonstrates notable translational efficiency. It serves as a promising tool in molecular biology, applicable in mRNA vaccines and transfection processes, including protein production, gene therapy, and anti-cancer immunization [1].

CO[C@@H]1[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OC)[C@@H]2OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c2[nH]c(N)nc3=O)n2cnc3c(N)ncnc23)O[C@H]([C@@H]1O)n1c[n+](C)c2c1[nH]c(N)nc2=O