β-Glucuronide-dPBD-PEG5-NH2 TFA

β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer used in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-dPBD, employing a cleavable β-glucuronide linkage. It serves as a proagent to reduce side effects, induce apoptosis, and arrest the cell cycle, exhibiting antitumor activity [1].

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