Biotinylated-JQ1
Product Specifications
CAS Number
1635437-52-3
Target
Others, Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
Biotinylated-JQ1 (Biotin-JQ1), a biotinylated derivative of JQ1, selectively binds to the BRD4 bromodomain with high affinity. It effectively inhibits the proliferation of MM1.S multiple myeloma cells, demonstrating an EC50 of 0.4 μM [1].
Smiles
CC=1C2=C(N3C([C@H](CC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)=O)N=C2C6=CC=C(Cl)C=C6)=NN=C3C)SC1C
Molecular Formula
C39H53ClN8O6S2
Molecular Weight
829.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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ING1 (Inhibitor of Growth Family, Member 1, OTTHUMP00000018703, OTTHUMP00000018704, OTTHUMP00000018705, OTTHUMP00000018706, Growth Inhibitor ING1, Growth Inhibitory Protein ING1, Inhibitor of Growth 1, Tumor suppressor ING1, p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a) (MaxLight 405) discontinued
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