Biotinylated-JQ1
Product Specifications
CAS Number
1635437-52-3
Target
Others|||Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic|||Others
Bioactivity
Biotinylated-JQ1 (Biotin-JQ1), a biotinylated derivative of JQ1, selectively binds to the BRD4 bromodomain with high affinity. It effectively inhibits the proliferation of MM1.S multiple myeloma cells, demonstrating an EC50 of 0.4 ?M [1].
Smiles
CC=1C2=C(N3C([C@H](CC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)=O)N=C2C6=CC=C(Cl)C=C6)=NN=C3C)SC1C
Molecular Formula
C39H53ClN8O6S2
Molecular Weight
829.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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