KT-474
Product Specifications
CAS Number
2432994-31-3
Target
PROTACs, Apoptosis, IRAK
Related Pathways
Apoptosis, NF-κB, Immunology/Inflammation, PROTAC
Purity
0.9957
Bioactivity
KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.
Smiles
O=C1N(C=2C(=C(C#CCOC3CCN(C[C@H]4CC[C@@H](CC4)N5C=C(NC(=O)C6=C7N(N=C6)C=CC(=N7)N8[C@@]9(C[C@](C8)(OC9)[H])[H])C(C(F)F)=N5)CC3)C=CC2)N1C)C%10C(=O)NC(=O)CC%10
Molecular Formula
C44H49F2N11O6
Molecular Weight
865.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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