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OARV-771

Product Specifications

CAS Number

2683008-37-7

Target

PROTACs, Epigenetic Reader Domain

Related Pathways

PROTAC, Chromatin/Epigenetic

Bioactivity

OARV-771, a VHL-based BET degrader (PROTAC) featuring enhanced cell permeability, demonstrates DC50 values of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3, respectively [1].

Smiles

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCCOCCOC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

Molecular Formula

C49H59ClN8O8S2

Molecular Weight

987.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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