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Chol-CTPP

Product Specifications

Target

Others, Apoptosis, Reactive Oxygen Species

Related Pathways

Metabolism, Immunology/Inflammation, Others, NF-κB, Apoptosis

Bioactivity

Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP) . Lip-CTPP emerges as a potential carrier facilitating the collaborative anti-glioma efficacy of doxorubicin (DOX) and lonidamine (LND) . It significantly enhances the inhibition of tumor cell proliferation, migration, and invasion, promotes apoptosis and necrosis, and disrupts mitochondrial function [1].

Molecular Formula

C144H263N3O53

Molecular Weight

2884.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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