Chol-CTPP
Product Specifications
Target
Others, Apoptosis, Reactive Oxygen Species
Related Pathways
Metabolism, Immunology/Inflammation, Others, NF-κB, Apoptosis
Bioactivity
Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP) . Lip-CTPP emerges as a potential carrier facilitating the collaborative anti-glioma efficacy of doxorubicin (DOX) and lonidamine (LND) . It significantly enhances the inhibition of tumor cell proliferation, migration, and invasion, promotes apoptosis and necrosis, and disrupts mitochondrial function [1].
Molecular Formula
C144H263N3O53
Molecular Weight
2884.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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