MS5033
Product Specifications
CAS Number
2376137-29-8
Target
Others, Akt, PROTACs
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, PROTAC, Others
Bioactivity
MS5033 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades AKT (also known as protein kinase B), exhibiting a half-maximal degradation concentration (DC50) of 430 nM in PC3 cells [1].
Smiles
NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCN1CCN(CC1)C(=O)CCOCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)c1ccc(Cl)cc1
Molecular Formula
C51H66ClN11O11
Molecular Weight
1044.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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