Protease-Activated Receptor-1 antagonist 2
Product Specifications
CAS Number
1454588-34-1
Target
Others, Protease-activated Receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic characteristics, making it valuable in cardiovascular disease (CVD) research, including studies on atherosclerosis and restenosis [1].
Smiles
[H][C@@]12[C@@H](C)OC(=O)[C@]1(N)CC(F)(F)[C@@H](C)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N
Molecular Formula
C24H23F2N3O2
Molecular Weight
423.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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