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Protease-Activated Receptor-1 antagonist 2

Product Specifications

CAS Number

1454588-34-1

Target

Others, Protease-activated Receptor

Related Pathways

GPCR/G Protein, Others

Bioactivity

Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic characteristics, making it valuable in cardiovascular disease (CVD) research, including studies on atherosclerosis and restenosis [1].

Smiles

[H][C@@]12[C@@H](C)OC(=O)[C@]1(N)CC(F)(F)[C@@H](C)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N

Molecular Formula

C24H23F2N3O2

Molecular Weight

423.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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