ROS-ERS inducer 1

ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt (II) -N-heterocyclic carbene (Pt (II) -NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reactive oxygen species (ROS) generation, leading to the release of damage-associated molecular patterns (DAMPs) in HCC cells, showcasing significantly higher anticancer activities than Cisplatin [1].