EGFR-IN-22

Product Specifications

CAS Number

2634646-14-1

Target

Others, EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Others, Angiogenesis, JAK/STAT signaling

Bioactivity

EGFR-IN-22 is a highly effective inhibitor targeting wild type EGFR and its mutant form, EGFR L858R/T790M/C797S, displaying IC50 values of 4.91 nM and 0.54 nM, respectively.

Smiles

COc1cc(N2CCC3(CC2)CCN(CC3)C(C)(C)CF)c(cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)-c1cnn(C)c1

Molecular Formula

C38H47BrFN10O2P

Molecular Weight

805.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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