EGFR-IN-22
Product Specifications
CAS Number
2634646-14-1
Target
Others, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Others, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR-IN-22 is a highly effective inhibitor targeting wild type EGFR and its mutant form, EGFR L858R/T790M/C797S, displaying IC50 values of 4.91 nM and 0.54 nM, respectively.
Smiles
COc1cc(N2CCC3(CC2)CCN(CC3)C(C)(C)CF)c(cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)-c1cnn(C)c1
Molecular Formula
C38H47BrFN10O2P
Molecular Weight
805.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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