Larsucosterol trimethylamine
Product Specifications
Target
Endogenous Metabolite, Liver X Receptor
Related Pathways
Metabolism
Purity
0.97
Bioactivity
Larsucosterol trimethylamine (DUR-928 trimethylamine) is a potent liver X receptor (LXR) antagonist that modulates endogenous epigenetics, reduces lipid accumulation in hepatocytes, attenuates lipopolysaccharide (LPS) and TNFα-induced inflammatory responses in macrophages, and alleviates LPS- and acetaminophen (ATMP) -induced multi-organ damage.
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C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]3[C@H]2CC=C4[C@]3(C)CC[C@H](OS(=O)(O)=O)C4)CCCC(C)(O)C.CN(C)C
Molecular Formula
C30H55NO5S
Molecular Weight
541.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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