PROTAC BRD4 Degrader-14
Product Specifications
Target
Epigenetic Reader Domain, PROTACs, Others
Related Pathways
PROTAC, Others, Chromatin/Epigenetic
Bioactivity
PROTAC BRD4 Degrader-14, a PROTAC (Proteolysis Targeting Chimera) linked by ligands to von Hippel-Lindau and BRD4, exhibits IC50 values of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. This compound effectively degrades the BRD4 protein in PC3 prostate cancer cells [1].
Molecular Formula
C57H61F2N9O11S2
Molecular Weight
1150.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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