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PROTAC BRD4 Degrader-14

Product Specifications

Target

Epigenetic Reader Domain, PROTACs, Others

Related Pathways

PROTAC, Others, Chromatin/Epigenetic

Bioactivity

PROTAC BRD4 Degrader-14, a PROTAC (Proteolysis Targeting Chimera) linked by ligands to von Hippel-Lindau and BRD4, exhibits IC50 values of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. This compound effectively degrades the BRD4 protein in PC3 prostate cancer cells [1].

Molecular Formula

C57H61F2N9O11S2

Molecular Weight

1150.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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