Roxatidine
Product Specifications
CAS Number
78273-80-0
Target
Others, p38 MAPK, Histamine Receptor, NF-κB, Caspase
Related Pathways
NF-κB, Others, Immunology/Inflammation, Proteases/Proteasome, Apoptosis, MAPK, GPCR/G Protein, Neuroscience
Bioactivity
Roxatidine, the active metabolite of Roxatidine acetate hydrochloride, serves as a histamine H2-receptor antagonist and exhibits anti-ulcer properties. It functions by suppressing the release of histamine, thereby inhibiting proton secretion, and also reduces the production of VEGF-1, a key indicator of inflammation and angiogenesis. This compound demonstrates an anti-allergic inflammatory effect [1].
Smiles
C(C1=CC(OCCCNC(CO)=O)=CC=C1)N2CCCCC2
Molecular Formula
C17H26N2O3
Molecular Weight
306.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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