Roxatidine
Product Specifications
CAS Number
78273-80-0
Target
Others|||p38 MAPK|||Histamine Receptor|||NF-?B|||Caspase
Related Pathways
NF-?B|||Others|||Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||MAPK|||GPCR/G Protein|||Neuroscience
Bioactivity
Roxatidine, the active metabolite of Roxatidine acetate hydrochloride, serves as a histamine H2-receptor antagonist and exhibits anti-ulcer properties. It functions by suppressing the release of histamine, thereby inhibiting proton secretion, and also reduces the production of VEGF-1, a key indicator of inflammation and angiogenesis. This compound demonstrates an anti-allergic inflammatory effect [1].
Smiles
C(C1=CC(OCCCNC(CO)=O)=CC=C1)N2CCCCC2
Molecular Formula
C17H26N2O3
Molecular Weight
306.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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