Bicuculline methochloride
Product Specifications
CAS Number
38641-83-7
Target
GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9935
Bioactivity
Bicuculline methochloride is a competitive GABAA receptor antagonist and allosteric inhibitor with an IC50 of 1.7 μM. It blocks Ca2+-dependent activation of potassium channels, exhibits convulsant activity, and is suitable for epilepsy research.
Smiles
C[N+]1(C)[C@]([C@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[Cl-]
Molecular Formula
C21H20ClNO6
Molecular Weight
417.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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