SJF620 hydrochloride

2821938-05-8

PROTACs, BTK

PROTAC, Tyrosine Kinase/Adaptors, Angiogenesis

SJF620 hydrochloride is a PROTAC that utilizes a lenalidomide analog to recruit CRBN and ligands to target Btk, exhibiting a DC50 of 7.9 nM [1].

NC1=C2C(=NN(C2=NC=N1)C3CCN(CCOCCOCCOC=4C=C5C(=CC4)C(=O)N(C5)C6C(=O)NC(=O)CC6)CC3)C7=CC=C(OC8=CC=CC=C8)C=C7.Cl

C41H45ClN8O7

797.3

Ice Packs

-20°C