SJF620 hydrochloride
Product Specifications
CAS Number
2821938-05-8
Target
PROTACs, BTK
Related Pathways
PROTAC, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
SJF620 hydrochloride is a PROTAC that utilizes a lenalidomide analog to recruit CRBN and ligands to target Btk, exhibiting a DC50 of 7.9 nM [1].
Smiles
NC1=C2C(=NN(C2=NC=N1)C3CCN(CCOCCOCCOC=4C=C5C(=CC4)C(=O)N(C5)C6C(=O)NC(=O)CC6)CC3)C7=CC=C(OC8=CC=CC=C8)C=C7.Cl
Molecular Formula
C41H45ClN8O7
Molecular Weight
797.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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