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INY-03-041 trihydrochloride

Product Specifications

Target

Akt, PROTACs

Related Pathways

Cytoskeletal Signaling, PROTAC, PI3K/Akt/mTOR signaling

Bioactivity

INY-03-041 trihydrochloride, a potent and highly selective PROTAC-based pan-AKT degrader, comprises Ipatasertib, an ATP-competitive AKT inhibitor, conjugated to Lenalidomide. It effectively inhibits AKT1, AKT2, and AKT3 with IC50 values of 2.0, 6.8, and 3.5 nM, respectively [1].

Molecular Formula

C44H59Cl4N7O5

Molecular Weight

907.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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