CP-547632 TFA
Product Specifications
CAS Number
2805804-54-8
Target
FGFR, VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
CP-547632 TFA is an orally active, ATP-competitive inhibitor that potently targets VEGFR-2 and FGF kinases with IC50 values of 11 nM and 9 nM, respectively. It demonstrates selectivity for VEGFR-2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs), exhibiting antitumor efficacy [1].
Molecular Formula
C22H25BrF5N5O5S
Molecular Weight
646.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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