PROTAC Bcl-xL degrader-1
Product Specifications
Target
Others|||Bcl-2 Family|||PROTACs
Related Pathways
Apoptosis|||PROTAC|||Others
Bioactivity
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits toxicity towards human platelets and MyLa 1929 cells, with IC50 values of 62 nM and 8.5 ?M, respectively [1].
Molecular Formula
C76H96ClF3N10O11S3
Molecular Weight
1514.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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