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Ep300/CREBBP-IN-8

Product Specifications

CAS Number

2259641-24-0

Target

Histone Acetyltransferase|||Others

Related Pathways

Others|||Chromatin/Epigenetic

Bioactivity

Ep300/CREBBP-IN-8 (Example 37), a potent and orally active inhibitor of Ep300 and CREBBP, shows IC50 values of 0.014 ?M and 0.018 ?M, respectively, and is utilized in cancer research [1].

Smiles

COc1ccc(cc1F)C1(CCCCC1)C(=O)N1C[C@H](F)C[C@@H]1C(=O)Nc1ccc2[nH]ncc2n1

Molecular Formula

C25H27F2N5O3

Molecular Weight

483.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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