α-Conotoxin Vc1.1 TFA

?-Conotoxin Vc1.1 TFA is a peptide isolated from Conus victoriae and a selective nAChR antagonist that inhibits ?3?5?2, ?3?2 and ?3?4, reversing mechanical allodynia in neuropathic pain models and can be used to study neuropathic chronic pain. ?-Conotoxin Vc1.1 TFA inhibits human dorsal root ganglion nerve excitability and mouse colon nociception via GABA (B) receptors.

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