Mesembrine
Product Specifications
CAS Number
468-53-1
Target
5-HT Receptor, Others, PDE
Related Pathways
Metabolism, Others, GPCR/G Protein, Neuroscience
Bioactivity
Mesembrine ((+) -Mesembrine), a primary alkaloid distinguished by its aryloctahydroindole structure, acts as a potent 5-HT transporter inhibitor with an inhibition constant (K i) of 1.4 nM. Additionally, it demonstrates inhibitory activity against phosphodiesterase 4B (PDE4B) with an inhibitory concentration 50% (IC50) of 7.8 μM [1] [2].
Smiles
[H][C@@]12CC(=O)CC[C@@]1(CCN2C)c1ccc(OC)c(OC)c1
Molecular Formula
C17H23NO3
Molecular Weight
289.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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