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Canakinumab

Product Specifications

CAS Number

914613-48-2

Target

IL Receptor, Interleukin

Related Pathways

Immunology/Inflammation

Purity

0.988

Bioactivity

Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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