Canakinumab
Product Specifications
CAS Number
914613-48-2
Target
IL Receptor, Interleukin
Related Pathways
Immunology/Inflammation
Purity
0.988
Bioactivity
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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