Canakinumab
Product Specifications
CAS Number
914613-48-2
Target
IL Receptor, Interleukin
Related Pathways
Immunology/Inflammation
Purity
0.988
Bioactivity
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
244805-APC 100 µL
CNOT2 (CCR4-NOT Transcription Complex, Subunit 2, CDC36, HSPC131, NOT2, NOT2H) (APC)
Sign In for Pricing
View Details 
YPD40662-01 50 mg
2- (3-Methoxy-2,2-dimethylcyclobutyl) acetic acid
Sign In for Pricing
View Details YPD40662-02 0.5 g
2- (3-Methoxy-2,2-dimethylcyclobutyl) acetic acid
Sign In for Pricing
View Details