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(R) -Lanicemine

Product Specifications

CAS Number

190581-71-6

Target

IGluR, Others

Related Pathways

Others, Neuroscience, Membrane transporter/Ion channel

Bioactivity

(R) -Lanicemine ((R) -AZD6765), the less active R-enantiomer of Lanicemine, is a low-trapping NMDA channel blocker. It exhibits a binding affinity (Ki) of 0.56-2.1 μM for the NMDA receptor and shows inhibitory concentrations (IC50s) of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. It has been associated with antidepressant effects [1].

Smiles

N[C@H](Cc1ccccn1)c1ccccc1

Molecular Formula

C13H14N2

Molecular Weight

198.26

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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