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(R) -Lanicemine

Product Specifications

Target

IGluR|||Others

Related Pathways

Others|||Neuroscience|||Membrane transporter/Ion channel

Bioactivity

(R) -Lanicemine ((R) -AZD6765), the less active R-enantiomer of Lanicemine, is a low-trapping NMDA channel blocker. It exhibits a binding affinity (Ki) of 0.56-2.1 ?M for the NMDA receptor and shows inhibitory concentrations (IC50s) of 4-7 ?M and 6.4 ?M in CHO and Xenopus oocyte cells, respectively. It has been associated with antidepressant effects [1].

Smiles

N[C@H](Cc1ccccn1)c1ccccc1

Molecular Formula

C13H14N2

Molecular Weight

198.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/64416005518000181/T73682

CAS Number

190581-71-6

Available Sizes

Curated Selection

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