(R) -Lanicemine
Product Specifications
CAS Number
190581-71-6
Target
IGluR, Others
Related Pathways
Others, Neuroscience, Membrane transporter/Ion channel
Bioactivity
(R) -Lanicemine ((R) -AZD6765), the less active R-enantiomer of Lanicemine, is a low-trapping NMDA channel blocker. It exhibits a binding affinity (Ki) of 0.56-2.1 μM for the NMDA receptor and shows inhibitory concentrations (IC50s) of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. It has been associated with antidepressant effects [1].
Smiles
N[C@H](Cc1ccccn1)c1ccccc1
Molecular Formula
C13H14N2
Molecular Weight
198.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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