Antibiotic DC 81
Product Specifications
CAS Number
81307-24-6
Target
Apoptosis|||Others|||DNA/RNA Synthesis|||Antibiotic
Related Pathways
Others|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology|||Apoptosis
Bioactivity
Antibiotic DC 81, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotic produced by Streptomyces species, acts as a potent inhibitor of nucleic acid synthesis. It specifically recognizes and binds to certain DNA sequences, forming a labile covalent adduct [1] [2].
Smiles
[H][C@@]12CCCN1C(=O)c1cc(OC)c(O)cc1N=C2
Molecular Formula
C13H14N2O3
Molecular Weight
246.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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