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Antibiotic DC 81

Product Specifications

CAS Number

81307-24-6

Target

Apoptosis|||Others|||DNA/RNA Synthesis|||Antibiotic

Related Pathways

Others|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology|||Apoptosis

Bioactivity

Antibiotic DC 81, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotic produced by Streptomyces species, acts as a potent inhibitor of nucleic acid synthesis. It specifically recognizes and binds to certain DNA sequences, forming a labile covalent adduct [1] [2].

Smiles

[H][C@@]12CCCN1C(=O)c1cc(OC)c(O)cc1N=C2

Molecular Formula

C13H14N2O3

Molecular Weight

246.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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