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Gefitinib N-oxide hydrochloride

Product Specifications

Target

EGFR|||Others

Related Pathways

JAK/STAT signaling|||Angiogenesis|||Others|||Tyrosine Kinase/Adaptors

Bioactivity

Gefitinib N-oxide hydrochloride, an N-oxide derivative of Gefitinib, acts as an EGFR tyrosine kinase inhibitor. Demonstrating an IC50 range of 2-37 nM in NR6wtEGFR cells, it emphasizes its efficacy in inhibiting the enzymatic activity of EGFR [1] [2].

Molecular Formula

C22H24ClFN4O41.5HCl

Molecular Weight

517.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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