PDS-0330
Product Specifications
CAS Number
2904682-19-3
Target
Others, Tight Junction Protein, Gap Junction Protein
Related Pathways
Others, Cytoskeletal Signaling
Purity
0.9993
Bioactivity
PDS-0330 is a claudin-1 small molecule inhibitor inhibitor.PDS-0330 inhibits claudin-1-dependent CRC progression and binds directly and specifically to claudin-1 with micromolar affinity.PDS-0330 exhibits well characterized pharmacokinetic properties with antitumor and Chemosensitizing activity.PDS-0330 interferes with claudin-1 / Src association to inhibit CRC progression and metastasis.
Smiles
N(C(NC(=O)C1=CC2=C(C=C1)C=CC=C2)=S)C3=CC=C(C4=NC=5C(O4)=CC=CC5)C=C3
Molecular Formula
C25H17N3O2S
Molecular Weight
423.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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