EB1
Product Specifications
CAS Number
42951-68-8
Target
Apoptosis, MNK, PERK
Related Pathways
Apoptosis, MAPK
Purity
0.9982
Bioactivity
EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.
Smiles
NC=1C2=C(C=C(N=C2NN1)C3=CC=CC=C3)C4=CC=CC=C4
Molecular Formula
C18H14N4
Molecular Weight
286.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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