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EB1

Product Specifications

CAS Number

42951-68-8

Target

Apoptosis, MNK, PERK

Related Pathways

Apoptosis, MAPK

Purity

0.9982

Bioactivity

EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.

Smiles

NC=1C2=C(C=C(N=C2NN1)C3=CC=CC=C3)C4=CC=CC=C4

Molecular Formula

C18H14N4

Molecular Weight

286.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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