TH470
Product Specifications
CAS Number
2834739-51-2
Target
Others, LIM Kinase
Related Pathways
Others, Cell Cycle/Checkpoint
Bioactivity
TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2, making it applicable in orphan disease research.
Smiles
S(NC1=CC=CC=C1)(=O)(=O)C2=CC=C(C(N(CC3=CC=CC=C3)CCNC(=O)C=4SC(NC(C(C)C)=O)=NC4)=O)C=C2
Molecular Formula
C30H31N5O5S2
Molecular Weight
605.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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