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JO146

Product Specifications

CAS Number

130727-21-8

Target

Serine Protease, Others

Related Pathways

Others, Proteases/Proteasome

Bioactivity

JO146 is a protease inhibitor for Chlamydia trachomatis high temperature requirement A (CtHtrA) and human neutrophil elastase (HNE), with IC50 values of 21.86 μM for CtHtrA and 1.15 μM for HNE, respectively. It is effective in inhibiting bacterial infections.

Smiles

P(C(NC(=O)[C@H]1N(C([C@@H](NC(OC(C)(C)C)=O)[C@H](C)C)=O)CCC1)C(C)C)(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O

Molecular Formula

C31H44N3O7P

Molecular Weight

601.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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