JO146
Product Specifications
CAS Number
130727-21-8
Target
Serine Protease, Others
Related Pathways
Others, Proteases/Proteasome
Bioactivity
JO146 is a protease inhibitor for Chlamydia trachomatis high temperature requirement A (CtHtrA) and human neutrophil elastase (HNE), with IC50 values of 21.86 μM for CtHtrA and 1.15 μM for HNE, respectively. It is effective in inhibiting bacterial infections.
Smiles
P(C(NC(=O)[C@H]1N(C([C@@H](NC(OC(C)(C)C)=O)[C@H](C)C)=O)CCC1)C(C)C)(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O
Molecular Formula
C31H44N3O7P
Molecular Weight
601.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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