TNG260
Product Specifications
CAS Number
2935964-98-8
Target
Others
Related Pathways
Others
Bioactivity
TNG260 is a CoREST-selective deacetylase (CoreDAC) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3 . TNG260 leads to HDAC1 inhibition, reverses anti-PD1 resistance driven by loss of STK11. TNG260 decreases intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killing .
Smiles
N(C(=O)C1=CC=C(S(C)(=N)=O)C=C1)C=2C=C(C=CC2N)C3=CC=C(F)C=C3
Molecular Formula
C20H18FN3O2S
Molecular Weight
383.439
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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