RK-701
Product Specifications
CAS Number
2648855-18-7
Target
Histone Methyltransferase|||Others
Related Pathways
Others|||Chromatin/Epigenetic
Bioactivity
RK-701, a highly selective and non-genotoxic G9a inhibitor, exhibits an IC 50 value of 23-27 nM. It selectively up-regulates HbF, ?-Globin, and BGLT3 expression while down-regulating H3K9me2 expression. Additionally, RK-701 inhibits BCL11A and ZBTB7A.
Smiles
CC=1C2=C(NC1C(N[C@H](C(NC3=CC=C(C#N)C=C3)=O)CCC4CC4)=O)CC(C)(C)CC2=O
Molecular Formula
C26H30N4O3
Molecular Weight
446.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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