ZC0109
Product Specifications
Target
Others|||Apoptosis|||Indoleamine 2,3-Dioxygenase (IDO) |||IDO
Related Pathways
Metabolism|||Apoptosis|||Others
Bioactivity
ZC0109, a dual inhibitor targeting IDO1 and Thioredoxin Reductase 1 (TrxR1) with IC50 values of 50 nM and 3.0 ?M respectively, effectively promotes ROS accumulation and arrests the cell cycle at the G1/S phase, culminating in apoptosis of cancer cells.
Smiles
O=C(CC1=CC=C(O)C=C1)NC1=NN=C(CCCNC2=NON=C2/C(=N/O)NC2=CC(Br)=C(F)C=C2)S1
Molecular Formula
C22H20BrFN8O4S
Molecular Weight
591.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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