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MR2938

Product Specifications

CAS Number

1044870-65-6

Target

JNK, NF-κB, Cholinesterase (ChE), NOD-like Receptor (NLR), Others, CCR, Interleukin, TNF, NO Synthase

Related Pathways

Apoptosis, Microbiology/Virology, GPCR/G Protein, Others, NF-κB, Immunology/Inflammation, Neuroscience, MAPK

Bioactivity

MR2938 is a potent acetylcholinesterase (AChE) inhibitor, evidenced by an IC50 value of 5.04 μM, and significantly inhibits nitric oxide (NO) production with an IC50 of 3.29 μM. Additionally, it mitigates neuroinflammation by blocking the MAPK/JNK and NF-κB signaling pathways, making it a promising compound for Alzheimer's disease (AD) research.

Smiles

O(C)C1=C2C(NC(=NC2=O)C3=CC=C(C=C3)N4CCN(C)CC4)=CC(OC)=C1

Molecular Formula

C21H24N4O3

Molecular Weight

380.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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