MR2938
Product Specifications
CAS Number
1044870-65-6
Target
JNK|||NF-?B|||Cholinesterase (ChE) |||NOD-like Receptor (NLR) |||Others|||CCR|||Interleukin|||TNF|||NO Synthase
Related Pathways
Apoptosis|||Microbiology/Virology|||GPCR/G Protein|||Others|||NF-?B|||Immunology/Inflammation|||Neuroscience|||MAPK
Bioactivity
MR2938 is a potent acetylcholinesterase (AChE) inhibitor, evidenced by an IC50 value of 5.04 ?M, and significantly inhibits nitric oxide (NO) production with an IC50 of 3.29 ?M. Additionally, it mitigates neuroinflammation by blocking the MAPK/JNK and NF-?B signaling pathways, making it a promising compound for Alzheimer's disease (AD) research.
Smiles
O(C)C1=C2C(NC(=NC2=O)C3=CC=C(C=C3)N4CCN(C)CC4)=CC(OC)=C1
Molecular Formula
C21H24N4O3
Molecular Weight
380.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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