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BT-GSI

Product Specifications

Target

Others|||Gamma-secretase

Related Pathways

Others|||Stem Cells|||Proteases/Proteasome|||Neuroscience

Bioactivity

BT-GSI, a ?-secretase inhibitor (GSI) with bone-targeting capabilities, effectively inhibits Notch signaling. Exhibiting dual action, it possesses both anti-myeloma and anti-resorptive properties, making it a promising candidate for research into multiple myeloma and related bone diseases. Additionally, BT-GSI demonstrates potential in inhibiting tumor growth and the progression of osteolytic disease.

Smiles

CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)/C=N/N(C)CCCC(=O)NC(P(=O)(O)O)P(=O)(O)O)NC(=O)OCC1=CC=CC=C1.Br

Molecular Formula

C26H46BrN5O10P2

Molecular Weight

730.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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